Rati Kailash Prasad Tripathi

Synthesis, Pharmacological Evaluation, Molecular Docking, and In Silico ADMET Profiling of Novel Ibuprofen–Chalcone Hybrids as Potent Anti-Inflammatory Agents

Abstract Objective: Conventional nonsteroidal anti-inflammatory drugs (NSAIDs) are severely limited by systemic toxicities. To address these constraints, we designed and synthesized a novel series of ibuprofen–chalcone hybrid molecules, capitalizing on a molecular hybridization s...