Raphaël Scharfmann

Parallel regulation of tissue morphogenesis and cell fate specification by RAR:RXR signalling during pancreas formation

During embryogenesis, morphologically diverse epithelial organs bud from different regions of the embryonic gut. The unique features of each nascent organ result from distinct cell fate specification and morphogenetic events elicited by organ-inducing cues. Retinoic acid is a pow...