Randall J. Kimple

Window-of-Opportunity Study Utilizing Preoperative Cetuximab in Patients with Head and Neck Cancer

Abstract Purpose. AXL, is a receptor tyrosine kinase implicated in EGFR resistance. The primary objective of this study was to test the hypothesis, generated in preclinical studies, that low AXL correlates with clinical response to cetuximab in patients with head and neck cancer...