Ramin Nilforooshan

Applying a systemic approach that extends beyond the brain to Alzheimer’s disease pathogenesis

Traditional dementia research often isolates single aspects, biomarkers or symptoms, overlooking complex interactions shaping disease risk and progression. Lysosomal and mitochondrial dysfunction, reflecting systemic processes, may explain links between Alzheimer’s and metabolic,...

Are different consumer sleep technologies measuring the same essential aspects of sleep?

Abstract Study objectives Consumer sleep technologies (CSTs) enable low-burden longitudinal sleep monitoring, and their output measures are often interpreted as equivalent to polysomnography (PSG) measures. We applied a measurement reliability-aware approach to determine whether...