Rami Mhanna

Identification of Highly Cytotoxic Antisense Oligonucleotides Targeting Essential Genes in Human Ovarian and Lung Cancer Cells

Therapeutic nucleic acid (TNA)‐based gene silencing strategies, such as antisense oligonucleotides (ASOs), have been explored for cancer treatment. However, no ASO‐based anticancer drugs are currently available, largely because of limited therapeutic efficacy. Conventional ASO‐ba...