Ralf Jacob

Phosphoproteomics identifies the DYRK1B protein kinase as a regulator of processing bodies

ABSTRACT Dual-specificity tyrosine-phosphorylation-regulated kinase 1B (DYRK1B) modulates the cell cycle, cell fate during development, and is deregulated in cancer and metabolic syndrome. However, only a few DYRK1B substrates have been defined, so we undertook a phosphoproteomic...