Qiyue Guan

Targeted versus metagenomic next-generation sequencing in lower respiratory tract infection: complementary instruments and the interpretation problem that now limits clinical value

Objectives. To establish how targeted (tNGS) and metagenomic (mNGS) next-generation sequencing differ in analytical and diagnostic performance in lower respiratory tract infection (LRTI), how much of any difference is a property of the individual panel rather than of the platform...