Qiuxiang Tian

PolyAnalysis: a deep learning–based framework for nanopore-based poly(A) tail estimation and 3′-end regulation profiling

Abstract Background Polyadenylation at the 3′ end of mRNA regulates transcript stability, export, and translation, but poly(A) tail length and polyadenylation-site usage remain difficult to resolve from nanopore sequencing data because of homopolymer-associated errors and complex...