Qiu Zhong

Small extracellular vesicle-mediated epithelial–macrophage crosstalk contributes to macrophage dysfunction during PEDV infection

Abstract Mucosal immune defense depends on coordinated communication between epithelial and immune cells, yet pathogens can disrupt this crosstalk through diverse mechanisms. Here we show that porcine epidemic diarrhea virus (PEDV), an enteric alphacoronavirus, reshapes epithelia...