Qinqin Yan

Cascade Spirocyclization–Difunctionalization or Rearrangement of Bicyclobutyl-Tethered Aldehyde Hydrazones via Strain Release

Abstract A cascade spirocyclization–difunctionalization of bicyclobutyl-tethered aldehyde hydrazones with N-halosuccinimides was smoothly performed to access diverse halo-succinimide-containing diazaspiro[3.3]heptan-3-ones. Meanwhile, the three-component rearrangement of bicyclob...