Qingwei Zhang

Multisystem involvement in extramedullary plasmacytoma: diagnostic challenges and clinical implications—a case report

Extramedullary plasmacytoma (EMP) represents 3–5% of plasma cell tumors and is commonly found in the head and neck region, upper respiratory tract, and gastrointestinal tract. Cardiac and primary lung parenchymal involvement are extremely rare. This case report describes an unusu...

Targeting the ANKRD54/ELOVL6 axis suppresses malignancy in BRAF mutant colorectal cancer by disrupting fatty acid metabolism and promoting ferroptosis

Abstract Background BRAF-mutant (BRAF-MT) colorectal cancer (CRC) represents a clinically aggressive subtype characterized by distinct biological features and significantly worse prognosis compared to BRAF wild-type (BRAF-WT) CRC, with median survival reduced by approximately 40%...