Qingfeng Guo

Preparation and in vitro evaluation of amphotericin B-chondroitin sulfate polymer prodrug

Amphotericin B (AmB) remains the gold-standard antifungal agent, yet its clinical utility is severely limited by dose-dependent hemolytic and nephrotoxic side effects arising from its aggregation-prone nature and non-selective membrane binding. To address this challenge, we devel...