Qin Li

Epididymal Versus Testicular Sperm for ICSI in Obstructive Azoospermia: Embryological, Clinical, and Neonatal Outcomes in a Retrospective Cohort

BACKGROUND: Whether sperm source influences intracytoplasmic sperm injection (ICSI) outcomes in men with obstructive azoospermia (OA) remains uncertain. OBJECTIVE: To compare embryological, clinical, and neonatal outcomes of ICSI using percutaneous epididymal sperm aspiration (PE...

Efficacy, safety, and pharmacokinetics of pumecitinib nasal spray for moderate-to-severe seasonal allergic rhinitis: a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial

Background Seasonal allergic rhinitis (SAR) is a pollen-triggered condition causing nasal inflammation and quality of life impairment. Pumecitinib, a topical Janus kinase (JAK) inhibitor may modulate allergic inflammation. We evaluated the efficacy, safety, and pharmacokinetics o...