Qin Li

The SIMDA framework maps PIP2-binding sites regulating the KCNQ1 channel

Voltage-gated potassium channel KCNQ1 (Kv7.1) underpins cardiac repolarization, epithelial ion transport, and inner ear function. Its versatility arises from interactions with KCNE proteins, calmodulin (CaM), and the lipid phosphatidylinositol 4,5-bisphosphate (PIP2), yet the mol...

Novel Hydrazide-Based Ionic Liquid Aqueous SolutionsRealize CO2 Capture through the Multisite Synergistic Actionof N and O Atoms

Abstract A new strategy for enhancing the hydrazine structure based on the inductive effect and conjugation effect of strong electron-withdrawing groups has been designed to effectively absorb CO2 with hydrazide-based ionic liquids (ILs). All three ILs aqueous solutions (diethyle...