Qijing Wu

Mitochondrial YME1L Restrains GRP75-Dependent ISR Activation to Prevent Podocyte Senescence in Diabetic Kidney Disease

Diabetic kidney disease (DKD) is characterized by progressive podocyte loss and cellular senescence, but the upstream stress pathways that determine podocyte fate are not fully understood. YME1L expression was markedly reduced in experimental models of DKD and was inversely assoc...