Qianye Zhang

CD80-targeted songorine nanotherapy restores PINK1-dependent mitophagy in proinflammatory macrophages for osteoarthritis treatment

Synovial macrophage-mediated inflammation and mitochondrial dysfunction are increasingly implicated in osteoarthritis (OA) progression, yet targeted restoration of mitochondrial quality control remains challenging. Here, we developed a macrophage-targeted, targeted delivery nanop...