Qi Lei

Engineering Nanoparticles to Navigate Biological Barriers for Deep Tumor Penetration

Deep and spatially uniform drug delivery remains a major challenge in nanomedicine for solid tumor therapy. During delivery, nanoparticles must sequentially traverse multiple biological barriers, from systemic circulation and tumor accumulation to vascular extravasation, basement...

Quaternary Phosphonium Salt Functionalization of Polyamide Reverse Osmosis Membranes: Effects on Separation Performance

Abstract Biofouling is a persistent challenge in reverse osmosis (RO) desalination and water reuse because it accelerates flux decline, increases energy consumption, and drives chemical cleaning requirements. Developing durable antibiofouling interfaces is therefore critical for...