Pragnesh B Parmar

Circadian biology and sexual offending: A hypothesis integrating chronobiological rhythms with Routine Activity Theory

Human behavior is temporally organized by endogenous circadian systems and by environmental and social schedules. Sexual motivation, sleep-wake regulation, endocrine function, cognition, and affective processes show time-dependent variation, while criminological research demonstr...

Endothelial Plasticity as a Continuum in the Tumor Microenvironment

The tumor microenvironment (TME) is a dynamic and complex ecosystem in which endothelial cells (ECs) play a central role beyond their traditional function as passive vascular conduits. Increasing evidence indicates that tumor-associated endothelial cells (TECs) undergo profound p...

Miller's Pyramid: Origin, Application, Advantages, Disadvantages, and Impact in Forensic Pathology Teaching

Introduction Competency-based medical education (CBME) emphasizes demonstrable competencies rather than time-based training. Miller's Pyramid remains an influential framework for conceptualizing clinical competence, but its contemporary application in forensic pathology education...