Pradyumna Pradhan

Batch correction reshapes dual-transition gene lists in confounded GTEx-TCGA prostate RNA-seq

Studying prostate field cancerization requires comparing truly healthy tissue against adjacent normal and tumor samples. Combining GTEx healthy prostate tissue with TCGA cancer data provides that three-group comparison; however, the design is fully confounded: every healthy sampl...

Batch correction reshapes dual-transition gene lists in confounded GTEx-TCGA prostate RNA-seq

Studying prostate field cancerization requires comparing truly healthy tissue against adjacent normal and tumor samples. Combining GTEx healthy prostate tissue with TCGA cancer data provides that three-group comparison; however, the design is fully confounded: every healthy sampl...