Poul Nissen

Double periodicity of the AnkyrinG-associated complex in the axon initial segment

The axon initial segment (AIS), situated within the first 20 to 60 µm of the axon, is essential for action potential generation and maintenance of axonal identity [M. N. Rasband, Nat. Rev. Neurosci. 11 , 552–562 (2010)]. Its structure relies on the beta (β)-IV-spectrin/AnkyrinG (...