Placido Bruzzaniti

Focused Ultrasound-Mediated Blood–Brain Barrier Opening for Enhanced Drug Delivery in Diffuse Gliomas: A Systematic Review

Background/Objectives: The blood–brain barrier (BBB) severely limits the intratumoral delivery of systemically administered therapeutics in diffuse gliomas, including glioblastoma (GBM), contributing to the persistently poor prognosis of these tumors. Focused ultrasound (FUS) com...