Piotr R. Stempinski

Genetic determinants that permit growth without the core septin Cdc12 in Cryptococcus neoformans

Septins are conserved cytoskeletal GTPases that regulate morphogenesis, cytokinesis, and cell-surface organization in fungi. In most model and pathogenic yeasts, including Saccharomyces cerevisiae and Candida albicans, core septin subunits such as Cdc3 and Cdc12 are essential and...