Piotr Paweł Chmielewski

Is Aging a Failure to Resolve? Integrating Damage Responses, Regenerative Decline, and Geroscience Interventions

Biological aging is accompanied by persistent tissue-damage signaling, chronic inflammation, extracellular matrix remodeling, cellular senescence, and declining regenerative capacity. Taken together, these features resemble an injury response that is repeatedly initiated but fail...