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3D DNA Framework-Encoded Multicolor DNA Amplifiers Permit Dual-Modal Simultaneous Imaging of Intracellular Multiplexed mRNAs

Abstract High-sensitivity, simultaneous visualization of multiple low-abundance intracellular mRNAs is appealed to elucidating their synergistic functions and guiding cancer diagnosis and treatment. Engineered nanoprobes integrating anti-enzymatic degradation, efficient signal am...