Pimrapat Gebert

Autoantibodies targeting G protein-coupled receptors and clinical outcome after ischemic stroke (PROSCIS-B)

Abstract Background G protein-coupled receptor (GPCR) directed regulatory autoantibodies (RABs) have previously been linked to poor functional outcome after ischemic stroke. We investigated the impact of anti-α1/α2/β1/β2 receptor, endothelin B receptor, angiotensin II receptor ty...

Imputing longitudinal PROM data at the item and score level in clinical trials

Abstract Background Missing data in patient-reported outcome measures (PROMs) can affect estimation accuracy and inferential validity, particularly under missing-at-random (MAR) mechanisms. Multiple imputation (MI) is commonly recommended, but the relative performance of item-lev...