Pietro Ruggieri

Bone marrow myeloid skewing and preserved immunoregulation in hip osteoarthritis of elderly patients

Abstract Osteoarthritis (OA) is increasingly recognized as a disease involving low-grade inflammation and immune remodeling, yet the contribution of the bone marrow (BM) myeloid compartment to hip OA remains poorly defined. Myeloid-derived suppressor cells (MDSCs) are immature my...

Estimating the Extent of Missed Opportunities for Osteoporosis Treatment Before Hip Fracture Occurrence

Abstract Hip fractures (HF) are among the most serious consequences of osteoporosis. Many individuals who subsequently sustain a HF may already fulfill recognized criteria for fracture risk assessment, bone mineral density (BMD) evaluation, or anti-osteoporosis treatment before t...