Phillip Byron Pope

Nonlinear network inference reveals two independent axes of ecological organisation in the rumen microbiome

Background The rumen microbiome is shaped by numerous external factors such as diet and host genetics, but these drivers act through internal microbial dynamics, including cross-feeding, substrate competition, and threshold-driven community shifts that give rise to non-linear int...

Integrative holo-omic data analysis predicts interactions across the host-microbiome axis

Understanding the interplay between host organisms and their microbiomes is central to the development of sustainable food systems. However, high dimensionality and spurious associations remain major obstacles to extracting meaningful biological insight from multi-omic host-assoc...