PhD Lavanya Sirigala MDS

Study on Subcellular Expression Patterns of p62/SQSTM1 in Oral Squamous Cell Carcinomas: An Immunohistochemical Analysis

ABSTRACT Background p62/SQSTM1 is a multifunctional 62 kDa protein that shuttles between the nucleus and cytoplasm to maintain protein homeostasis through the autophagy machinery. Dysregulated p62 acts as an oncogenic signalling hub, activating pathways such as NF-κB, Nrf2, and m...