Peter D. A. Shepherd

HO-1 Nuclear Interactome Implications in Neuroendocrine Transdifferentiation in Prostate Cancer

Neuroendocrine prostate cancer (NEPC) is characterized by androgen receptor (AR) independence and poor response to conventional therapies, highlighting the need to unveil the molecular mechanisms behind NEPC. We previously showed that heme oxygenase 1 (HO-1, encoded by HMOX1) tra...