Pera Panprom

Randomized generic-sequence crossover pharmacokinetic study of innovator and two generic tacrolimus formulations in kidney transplant recipients according to CYP3A inhibitor co-administration

Tacrolimus is a narrow therapeutic index immunosuppressant widely used in kidney transplantation. Although generic formulations reduce treatment costs, pharmacokinetic comparability under CYP3A inhibitor co-administration remains insufficiently studied. We conducted a prospective...