Pengli Zhang

Differential modulation of ferroptosis pathways by NOX1/4 and NLRP3 inhibition in DSS-induced colitis

Ferroptosis contributes to the pathogenesis of inflammatory bowel disease, but how NOX1/4 and NLRP3 pathways regulate this process remains unclear. This study aimed to investigate the therapeutic effects and mechanisms of the NOX1/4 inhibitor Setanaxib (SET) and the NLRP3 inhibit...