Peng Ke

Clinical outcomes and molecular features of CEBPA-mutated MPAL: a multi-center case series

Mixed phenotype acute leukemia (MPAL) is rare and aggressive, with no standard therapy. CEBPA mutations define favorable-risk AML, but their significance in MPAL is unknown. We reviewed eight CEBPA -mutated MPAL patients from five Chinese centers. Four received allo-HSCT in first...

Isolated Myeloid Sarcoma of the Thoracic Spine as Initial Presentation of Acute Promyelocytic Leukemia: A Case Report and Literature Review

Introduction: Acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia, typically presents with severe bleeding. However, the occurrence of APL with isolated myeloid sarcoma (MS) as the sole initial presentation is extremely rare, lacking typical clinical and labor...