Peng Guo

Breviscapine Blunts Hypertrophic Scar Formation via Dual Suppression of TGF-β1 Signaling and the Akt-mTOR Pathway

Background: Hypertrophic scar (HS) arises from aberrant cutaneous wound healing, characterized by uncontrolled myofibroblast proliferation and disproportionate extracellular matrix (ECM) accumulation. Breviscapine, a natural compound, suppresses inflammation and fibrosis. This st...