Peiwei Chai

Multiomics analysis reveals super enhancer associated GTSF1 and Schwann cell heterogeneity in neuroblastoma

Super-enhancers (SEs) contribute to oncogenic transcriptional programs in neuroblastoma (NB), but their relationship with nerve-associated microenvironmental remodeling remains unclear. This study integrated epigenomic, transcriptomic, dependency, single-cell, and clinical valida...