Peiling Zhu

Citrullination-associated transcriptional states identify a non-canonical invasive program in malignant epithelial cells and correlate with SPP1-CD44 immune microenvironment niches in thyroid cancer

Background Citrullination, a post-translational modification catalyzed by protein arginine deiminases (PADIs), has been implicated in malignant progression across multiple cancer types. However, its cellular distribution, functional significance, and role in microenvironment remo...