Pei-Qin Liao

Controlling the Reactivity of 1,3-Diacyl-2-gold Carbenes: [3+2] Annulation with External Imines over Wolff Rearrangement

Abstract Novel [3+2] annulations between imines and 1,3-diacyl gold carbenes have been developed to provide 2-acyl-3-aminopyrrole derivatives efficiently. Mechanistic studies suggest that the reaction is initiated by nucleophilic addition of the imine to the 1,3-diacyl gold carbe...