Pedro N. Leão

Trichlorination by a single cyanobacterial halogenase in the biosynthesis of lebomboamide A

Halogenation is a widely used strategy, both in nature and medicinal chemistry, to modulate the properties of small molecules. Cyanobacteria are a rich source of halogenases that act regio- and stereoselectively on sp3-hybridized carbon centers, which have been reported to cataly...