Paul R. Kasher

EXPRESS: caADAMTS13 reduces neutrophil-mediated vascular inflammation without exacerbating bleeding in experimental intracerebral haemorrhage

Targeting thromboinflammation through the von Willebrand factor (VWF)/ADAMTS13 axis is a promising therapeutic target for acute ischaemic stroke (AIS). Constitutively active ADAMTS13 (caADAMTS13) is a novel thrombolytic that improves outcomes in experimental AIS, with enhanced th...