Paul L. Fidel

The Story behind the Science: Solving the riddle for the pathogenesis of vulvovaginal candidiasis

ABSTRACT For nearly three decades, the pathogenesis of vulvovaginal candidiasis (VVC) remained an enigma. During the HIV/AIDS epidemic, observations that women with profound CD4 + T-cell deficiencies were not more susceptible to VVC challenged the prevailing assumption that prote...