Paul L. Bollyky

Dosing and delivery of bacteriophage therapy in a murine wound infection model

Lytic bacteriophages, viruses that lyse (kill) bacteria, hold great promise for treating infections, including wound infections caused by antimicrobial-resistant Pseudomonas aeruginosa. However, dosing and delivery strategies for phage therapy remain underdeveloped. In a mouse wo...

Isolation and genomic characterization of bacteriophage Luminis, a lytic Yuavirus infecting clinical strains of Pseudomonas aeruginosa

ABSTRACT We report the genome of Luminis, a lytic bacteriophage isolated from wastewater using Pseudomonas aeruginosa mPAO1Δpf4Δpf6. Phage Luminis is a Yuavirus with 61,617 bp of circularly permuted dsDNA and 64.4% GC content. In addition to reference strains, Luminis plaques on...