Patrick Kiefer

Antibiotic pretreatment with ampicillin or streptomycin differentially shapes Salmonella infection kinetics and associated intestinal inflammation in mice

Salmonella enterica serovar Typhimurium (S. Tm) mouse infection models commonly rely on antibiotic pretreatment to disrupt microbiota-mediated colonization resistance and enable reproducible infection. Streptomycin is the primary antibiotic used, but alternative pretreatment regi...