Pasi Virta

Multivalent RNA‐Cleaving Agents on a Cubic Octameric Silsesquioxane Core

ABSTRACT Selective RNA cleavage could provide versatile options in therapeutic applications. In this study, multivalent RNA‐cleaving agents, featuring 1,5,9‐triazacyclododecane or guanidine groups as catalytic centers, were synthesized on a cubic octameric silsesquioxane (COSS) c...