Päivi Lakkisto

MiR-145-5p modulates collagen production and fibroblast behaviour after cardiac injury partially via COL5A1

Abstract In contrast to humans, zebrafish hearts after cryoinjury undergo transient fibrotic scarring that subsequently resolves and renews with functional cardiomyocytes. To understand the molecular mechanisms underlying cardiac scarring and fibrotic resolution in zebrafish, we...