Ouided Benslama

Volatilome and derivatized metabolome via GC-MS of Heliotropium europaeum: antioxidant potential and anti-inflammatory activity with in-silico study

Abstract Heliotropium europaeum is a medicinal plant traditionally used for the treatment of inflammatory and skin disorders; however, t he volatile and derivatized metabolomic composition of the Algerian population remains largely unexplored. In this study, the volatile and deri...

Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation and ADMET Analysis Predict the Molecular Mechanisms of Gomisin N and Schisandrin B as Multi-Target Agents in Primary Sclerosing Cholangitis

Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammatory, fibrotic, and immune-mediated mechanisms, with limited therapeutic options. In this study, an integrative computational strategy combining network pharmacology, molecular do...