Noriaki Shimizu

Sustained NAD⁺ augmentation by high-dose nicotinamide mononucleotide supplementation in older adults: a 24-week randomized, double-blind, placebo-controlled trial

Abstract In animal studies, the administration of nicotinamide mononucleotide (NMN), a precursor of nicotinamide adenine dinucleotide (NAD⁺), can ameliorate aging-related diseases by increasing tissue and blood NAD⁺ levels. However, human data on this intervention are limited. In...