Nishte Rassol

Sex and age at exposure influence 131I biodistribution and dosimetry in Sprague–Dawley rats

Abstract Background Assessing the biodistribution and absorbed dose of ¹³¹I is crucial for optimisation of radionuclide therapy, as well as for improving risk assessment following nuclear emergencies. After the Chernobyl accident, an increase in thyroid cancer among children was...

Profiling proteomic responses in small intestinal neuroendocrine tumor GOT1 after [177Lu]Lu-DOTATATE therapy

Abstract Background Peptide receptor radionuclide therapy with [ 177 Lu]Lu-DOTATATE is an established treatment for somatostatin receptor–expressing neuroendocrine tumors. Although strong anti-tumor effects have been demonstrated in experimental models, curative responses in pati...