Ning Li

Modular Photocatalytic Three‐Component Gem ‐Difluoroalkylative Pyridylation of Alkenes via Pyridylphosphonium Salts

The difunctionalization of alkenes enables the efficient and simultaneous construction of two chemical bonds. However, methods for the simultaneous introduction of both a pyridine ring and a difluoromethyl group into alkene molecules remain scarce. Here, we report a strategy for...

hnRNPC facilitates coronavirus replication by directly binding the frameshift-stimulatory element of viral genomic RNA

Translation of key viral replicative proteins in coronaviruses requires a programmed –1 ribosomal frameshifting (–1 PRF) event controlled by the viral frameshift-stimulatory element (FSE). Although previous studies have analyzed host factor dependencies of coronaviruses, how host...