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Inclisiran-induced LDL-cholesterol reduction with and without concomitant statin therapy: a real-world analysis

Abstract Inclisiran lowers LDL-cholesterol (LDL-C) by inhibiting hepatic PCSK9 synthesis. Whether concomitant statin therapy modifies the magnitude of inclisiran-associated LDL-C reduction in routine clinical practice remains uncertain. In this retrospective single-center observa...