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Evolutionary Rewiring of Sugar Transporter Gene manXYZ Enables Highly Coordinated Non-glucose Metabolisms in Engineered Lactic Acid Bacterium

Abstract Achieving highly coordinated metabolism and efficient conversion of lignocellulose-derived non-glucose sugars remains a major challenge for biorefinery microbial cell factories. Herein, we report an evolutionary rewiring of an engineered lactic acid bacterium Pediococcus...