Nicole Y. Xin

Monocyte Chemoattractant Protein-1 Level Measured in Dried Blood Spots as a Biomarker for Diabetic Retinopathy

Purpose: To identify inflammatory proteins that differ between diabetic patients with and without retinopathy and to evaluate the feasibility of dried blood spots (DBSs) to measure monocyte chemoattractant protein-1 (MCP-1). Methods: In part I, we recruited 74 patients with diabe...

An exploratory study of the effect of metformin on the whole blood transcriptome of nondiabetic older adults with age-related macular degeneration

Abstract Metformin has received increasing attention for benefits beyond blood glucose lowering. The purpose of this study was to identify changes in whole blood transcriptome from a course of metformin in a randomized trial (NCT02684578) of nondiabetic older adults with age-rela...